Fig. 2

Dual-targeting ability of 4OI@iEC-M for macrophages and endothelial cells. (A) The iEC membrane was labeled with FITC (green) and the M1 membrane was labeled with DiD (red). The fluorescence images of HUVEC and RAW cells were shown after incubation with 4OI@iEC or 4OI@M (scale bar: 50 μm). (B) The fluorescence images of HUVEC and RAW cells were shown after incubation with 4OI@iEC-M (scale bar: 50 μm). (C) The relative green fluorescence intensity of HUVEC and RAW cells after incubation with 4OI@iEC and 4OI@iEC-M (**p < 0.01, n.s.: no significance). (D) The relative red fluorescence intensity of HUVEC and RAW cells after incubation with 4OI@M and 4OI@iEC-M (**p < 0.01, n.s.: no significance)