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Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: Bioinspired nanovesicles released from injectable hydrogels facilitate diabetic wound healing by regulating macrophage polarization and endothelial cell dysfunction

Fig. 4

Regulative effects of 4OI@iEC-M/GelMA on inflammation and macrophage polarization. (A-C) The proportions of M2 type (F4/80+, CD163+) and M1 type (F4/80+, iNOS+) macrophages in the control, GelMA, 4OI/GelMA, iEC-M/GelMA, and 4OI@iEC-M/GelMA groups (**p < 0.01, scale bar: 30 μm). (D) The protein level of M2 cytokines (IL-10) was detected by ELISA (**p < 0.01). (E) The protein level of M1 cytokines (IL-6) was detected by ELISA (**p < 0.01)

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