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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Bioinspired nanovesicles released from injectable hydrogels facilitate diabetic wound healing by regulating macrophage polarization and endothelial cell dysfunction

Fig. 5

4OI@iEC-M/GelMA promotes the functions and angiogenesis of endothelial cells. (A) The viability of HUVECs after incubation with control, GelMA, or 4OI@iEC-M/GelMA for 1, 2, and 3 days. (B) The HE staining of liver and kidney of the animal models in this study on wound repair day 9 (scale bar: 400 μm). (C, E) 4OI@iEC-M/GelMA group showed increased HUVEC tube formation (6 h) than other groups (**p < 0.01, scale bar: 200 μm). (D, F) Transwell assay (24 h) indicated that 4OI@iEC-M/GelMA group showed a higher migration rate than other groups (**p < 0.01, scale bar: 100 μm)

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