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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Targeting and repolarizing M2-like tumor-associated macrophage-mediated MR imaging and tumor immunotherapy by biomimetic nanoparticles

Fig. 2

Characterizations of HMMDN-Met@PM: (A) TEM image of SiO2, SiO2@mMnO2, HMMDN, HMMDN-Met@MM and HMMDN-Met@PM. Scale bars: 100 nm. (B) HAADF-STEM image and elemental mapping for HMMDN. (C) Pore-size distribution curve and N2 adsorption/desorption isotherms (inset) of HMMDN. (D) UV–vis absorption spectra of HMMDN, Met, HMMDN-Met, MM and HMMDN-Met@MM. (E) Hydrodynamic diameters of SiO2, SiO2@mMnO2, HMMDN, HMMDN-Met, HMMDN-Met@MM and HMMDN-Met@PM. (F) Zeta potential of SiO2, SiO2@mMnO2, HMMDN, HMMDN-Met, HMMDN-Met@MM and HMMDN-Met@PM. (G) The FT-IR spectra of DSPE-PEG-M2Pep, HMMDN, HMMDN-Met@MM and HMMDN-Met@PM. (H) The size measurement of HMMDN-Met@PM NPs in PBS versus time (Black line: Diameter; Red line: polydispersity index, PDI). (I) T1-weighted phantom images of HMMDN-Met@PM of different concentrations of Mn at different conditions using a 3.0 T MR scanner. (J) T1 relaxivity curves of HMMDN-Met@PM

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