Fig. 5
(A) T1-weighted and T1 pseudocolor images of different phenotypic macrophages treated with HMMDN-Met@PM(I), HMMDN-Met@MM(II), HMMDN-Met(III), PBS(IV); M0(a), M1(b) and M2(c). (B) Quantitative analysis of corresponding MRI signal intensity. (C) Fluorescence images observed the nanoparticle uptake in vitro after different phenotypic macrophages treated with different nanoparticles (scale bar: 20 μm). (D) Quantitative analysis of corresponding fluorescence intensity of C6. (E) Cell viability of 4T1 cells incubated with different nanoparticles/Met treated M2-like TAMs in transwell. (F) Specific lysis of 4T1 cell incubated with different nanoparticles/Met treated M2-like TAMs in transwell. (***P < 0.001)