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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Bone-targeting exosome nanoparticles activate Keap1 / Nrf2 / GPX4 signaling pathway to induce ferroptosis in osteosarcoma cells

Fig. 7

Therapeutic efficacy of BT-EXO-CAPin vivo. (A) The experimental schematic illustration. (B) Tumor growth curves of tumor volume following 21 days of various treatments. (C-D) Tumor images and weight of mice administrated various treatments following 21 days. (E) Immunoblot analysis of ACSL4, TFRC, FTH1, and GPC4. (F-G) Weight changes and survival rates of mice administered various treatments. (H) Representative pictures of HE staining of mice organs. (I) ELISA kit-based detection of ALT, AST, BUN, CREA, CK, and CK-MB levels. n = 6. ** p < 0.01, *** p < 0.001. Scale bar: H 100 μm

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Journal of Nanobiotechnology

ISSN: 1477-3155

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