Fig. 2
From: miRNAs derived from cobra venom exosomes contribute to the cobra envenomation
Injection of CV-exo-miR-2904 caused symptoms of cobra envenomation in mice. A Changes in mouse body temperature after injection with CV-exo-miR-2904 agomir. B Changes in mouse body weight 9 days after injection with CV-exo-miR-2904 agomir. C Liver tissue sections stained with hematoxylin and eosin after treatment with CV-exo-miR-2904 agomir. The scale bar represents 100 μm. D Immunohistochemical staining for Caspase 3 in liver tissue after injection with CV-exo-miR-2904 agomir. The scale bar represents 10 μm. E Volcano plot of significantly differentially expressed mRNAs between the agomir nc and CV-exo-miR-2904 agomir groups. F GO enrichment analysis of significantly differentially expressed mRNAs between the agomir nc and CV-exo-miR-2904 agomir groups. G KEGG pathway analysis of significantly differentially expressed mRNAs between the agomir nc and CV-exo-miR-2904 agomir groups. H GSEA of differentially expressed mRNAs between the agomir nc and CV-exo-miR-2904 agomir groups. Data are presented as mean ± SD. * represents P < 0.05. agomir nc agomir negative control