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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: Surface antibody changes protein corona both in human and mouse serum but not final opsonization and elimination of targeted polymeric nanoparticles

Fig. 3

Venn diagram and biological function of adsorbed murine and human proteins. The proteins adsorbed to the PNPs were detected by LC-MS/MS and classified according to their biological function (e.g., immune system involvement, complement activation, blood coagulation, apolipoproteins, histones, and others). The number and percentage of mouse proteins are shown in a Venn diagram (A). Proteins adsorbed only on uPNPs (B), those shared by the particles (C) and those present only on tPNPs (D) are shown by string analysis. The same was for human proteins: Venn diagram (E), proteins adsorbed to uPNPs (F) or shared by both particles (G) or present only on tPNPs (H). uPNPs: untargeted nanoparticles; tPNPs: targeted nanoparticles

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Journal of Nanobiotechnology

ISSN: 1477-3155

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