Fig. 4

Protective effect of 7CZ nanomedicines on subcellular organelles. a Stress fibers of human kidney podocytes were observed by CLSM after different treatments. The stress fibers were stained red, the nuclei were stained blue. Changes of the mitochondrial membrane potential (b), lysosome (c), endoplasmic reticulum (d) and golgi apparatus (e) in podocytes after different treatments. f Quantitative analysis of the fluorescence intensities by Image J to evaluate the restoration of lysosome after injury. Data are presented as mean ± SD, one-way ANOVA, ns, non-significance, *P < 0.05, **P < 0.01; ***P < 0.001, ****P < 0.0001, vs. ADR group