Fig. 8
Effects of anti-inflammatory hydrogels in the proliferative and remodeling phases of wound healing. (A) HE staining of the wound tissue reflected the thickness granulation tissue (green arrows) on day 21. Scale bar: 500 μm. Masson’s trichrome staining of the wound tissue reflected collagen deposition area on day 21. Scale bar: 100 μm. (B) Representative immunofluorescence staining images of CD31 reflected neovascularization. Scale bar: 100 μm. (C) Statistical data of collagen deposition area. (D) Statistical data of granulation tissue thickness. (E) Statistical data of CD31 positive area in the wound tissue. (n = 3; mean ± s.d.; *p < 0.05, **p < 0.01, ***p < 0.001)