Fig. 10

Bioinformatics analysis of the mechanism through which hUCMSC exosomes regulate HUVECs. a Top 100 miRNAs from three different datasets in the database, with the intersection taken. b Two algorithms, miRWalk2 and Starbase2, were used to predict mRNA, and the intersection was taken. c Visual results of GO analysis. d Bubble map of KEGG signaling pathways (gene count ≥ 5). e Interactions among 170 genes predicted based on the STRING database, with results visualized. f Western blot analysis of the involved signaling pathways. hUCMSCs, human umbilical cord mesenchymal stem cells. HUVECs, human umbilical vein endothelial cells