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Fig. 8 | Journal of Nanobiotechnology

Fig. 8

From: Biomineralized tetramethylpyrazine-loaded PCL/gelatin nanofibrous membrane promotes vascularization and bone regeneration of rat cranium defects

Fig. 8

New bone regeneration enhanced by PGHT membrane in a rat cranial defect model. A, B micro-CT scan images at 4 (A) and 8 (B) weeks post-surgery. The newly formed bone tissue is marked in red within the 5-mm diameter circle. C Bone mineral density (BMD). D Percent bone volume (BV/TV). E Trabecular number. F Connectivity density (Conn. Dn) (n = 8). *p < 0.05, **p < 0.01, ***p < 0.001, vs. defect alone with no implanted materials; #p < 0.05, ##p < 0.01, vs. PG membrane; &p < 0.05, &&p < 0.01, vs. PGH membrane

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