Table 2 Novel drug delivery carrier
Type of drug delivery vehicle | Drug delivery vehicle characteristics | References |
|---|---|---|
Nanoparticles | Advantages of small size, a large specific surface area, controllable morphology and easy modification Can effectively embed, adsorb or covalently crosslink hydrophilic/hydrophobic drug molecules Enhance the local concentration of drugs in the body | |
Liposomes | Are able to bind to a wide range of biologically active compounds when used as a drug delivery vehicle due to their inherent amphiphilic nature | |
Polymer | Encapsulate the drug in a specific part of the polymer Carry drugs by means of polymer-drug conjugation Employ targeting factors to load drugs for targeting to specific disease sites | |
Prodrugs | Produce synergistic effect Expand the scope of clinical applications Improve drug absorption Improved blood drug concentration drug efficacy is a function of drug concentration at the site of action Slow release at the administration site to achieve a prolonged action time | |
Targeting drug delivery system | Gives the drug a specific pharmacological activity Increases drug targeting ability and retention in target tissues Reduces drug toxicity to normal cells Improves the bioavailability of pharmaceutical formulations | |
Virus | High safety Low toxicity Contains marker genes |