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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Nanoengineered injectable hydrogels derived from layered double hydroxides and alginate for sustained release of protein therapeutics in tissue engineering applications

Fig. 7

Angiogenic potential of EPO-loaded hydrogels. A Images of the hydrogels placed in the CAM at 13 days of chick embryo. The angiogenic potential of the hydrogel formulation was examined by imaging at 15 and 17 days. Sustained release of EPO from the hydrogels induced the angiogenesis in a CAM assay. B Quantification of vascularized area and blood vessels. C Blood compatibility of the hydrogels was examined using hemolysis test. Inserted pictures are for RBCs treated with different hydrogels. D In situ injection of INHs into the subcutaneous region of albino mice. A bump appeared under the mouse’s skin immediately after the injection. Stability assessment of in situ formed hydrogels was examined by sacrificing the mice. Error bars in the graph represents mean ± SD (n = 3). Asterisks (*) denotes statistically significant differences. *P > 0.05; **P < 0.01; ***P < 0.001

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Journal of Nanobiotechnology

ISSN: 1477-3155

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