Fig. 1
From: Aptamer-based self-assembled nanomicelle enables efficient and targeted drug delivery
Characterization of C18-sgc8 and Ce6@C18-sgc8. a TEM images of the self-assembly of C18-sgc8 in water to form nanomicelles. b TEM mapping images of C18-sgc8. c DLS measurements of C18-sgc8 showing a median diameter of 38.8 nm. d DLS and PDI of C18-sgc8 nanometer micelles in water at 48 h. e Verification of the coupling of C18PMH and NH2-aptamers through 4% agarose gel electrophoresis. A buffer solution containing GelRed dye and NH2-sgc8 or C18-sgc8 was selected, followed by adding to the sample loading hole. After electrophoresis, agarose gel was used to select the GelRed channel in the imaging system for imaging: Lanes 1, sgc8 and 2, C18-sgc8. f DLS measurements of Ce6@C18-sgc8 in water (black) and PBS (red) micelles. g UV–vis spectra of Ce6, C18-sgc8 and Ce6@C18-sgc8. h Fluorescence spectra of Ce6, C18-sgc8 and Ce6@C18-sgc8