Fig. 6

NIR-II imaging and surgical navigation of peritoneal metastases of CRC. a White light and NIR-II imaging of the tumors exposed and after tumors excised in vivo. Abdominal ROI regions 1, 2, 3, and 4 were quantitively analyzed. Scale bar: 5 mm. b White light and NIR-II imaging of lesions resected under fluorescent navigation and suspicious lesions with supplemental biopsies ex vivo. Scale bar: 5 mm. c Fluorescence intensity statistics of ROI regions (1, 2, 3, and 4) of tumors exposed and after tumors excised in (a) (data are shown as mean ± SD). d. SBR of lesions of FGS compared to suspicious lesions of supplemental biopsies (SB) in (b) (data were shown as mean ± SD). e. Representative H&E staining images of tumors with different diameters (> 10 mm, 3 ~ 10 mm, and ≤ 3 mm), Scale bar: 100 μm. *p < 0.05, **p < 0.01, ***p < 0.001