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Table 2 NIR-II FGS diagnosis performance of FE-2PEG in different tumor diameters

From: High-precision detection and navigation surgery of colorectal cancer micrometastases

 

Nodule diameter

 

H&E

Sensitivity (95% CI)

Specificity (95% CI)

PPV (95% CI)

NPV (95% CI%)

Positive

Negative

NIR-II

> 10 mm

Positive

7

0

100

–

100

–

Negative

0

0

3 mm < nodule ≤ 10 mm

Positive

83

2

90.21 (84.03–96.40)

93.55 (84.39–102.71)

97.65 (94.36–100.94)

76.32 (62.15–90.48)

Negative

9

29

≤ 3 mm

Positive

220

9

96.07 (93.53–98.61)

82.35 (71.52–93.18)

96.07 (93.53–98.61)

82.35 (71.52–93.18)

Negative

9

42

  1. CI confidence limits, PPV positive predictive value, NPV negative predictive value