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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: PLGA nanoparticles engineering extracellular vesicles from human umbilical cord mesenchymal stem cells ameliorates polyethylene particles induced periprosthetic osteolysis

Fig. 2

Construction and characterization of PLGA-Exos. (A) TEM images of PLGA and PLGA-Exos. Scale bar, 200 nm. (B) Size distribution (PDI = 0.15, 0.18) and (C) zeta potential of PLGA and PLGA-Exos were measured by dynamic light scattering (n = 3). (D) Typical surface markers expressed on PLGA, Exos, and PLGA-Exos were determined by Western blot analysis (CD9: 25 kDa, CD63: 26 kDa, TSG101: 45 kDa). (E) Quantitative analyses of the releases of exosomes from PLGA-Exos and PLGA/Exos mixture over time. (F) Typical confocal images of RAW264.7 incubated with M2-BMSCs-Exos, (DiO-labeled Exos (green) and DII-labeled PLGA (red)). Scale bar, 10 μm

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Journal of Nanobiotechnology

ISSN: 1477-3155

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