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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Temperature sensitive nanogel-stabilized pickering emulsion of fluoroalkane for ultrasound guiding vascular embolization therapy

Fig. 5

Antitumor efficacies of TAE therapy and ultrasound imaging comparison of TGFPE, PNF10 dispersion, lipiodol and NS in VX2 tumor-bearing rabbits. a Schematic illustration of experiment schedule. b Color doppler and B-mode ultrasonography images in tumors before and at different points of time after being embolized by the above embolic material. The region surrounded by dotted red line is the embolized kidney. c The statistical analysis of B-mode ultrasound images. d CT images of tumors before and at different points of time after being embolized by the above embolic material. The region surrounded by dotted red line is the embolized tumor. e The statistical analysis of tumor sizes at 1 day before and after vascular embolization with the above embolic materials or the injection of NS. f The H&E stainning of tumor after vascular embolization with the above embolic materials for 2 weeks. (T) areas of tumor (L) liver tissue (N) areas of necrosis (M) tumor margins. g The statistical analysis of tumor necrosis rates after vascular embolization with the above embolic materials for 2 weeks. Scale = 2500 μm. n = 5, *P < 0.05, **P < 0.01, ***P < 0.001

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