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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: Nanocomposites based on nanoceria regulate the immune microenvironment for the treatment of polycystic ovary syndrome

Fig. 3

CeO2@RSV-induced macrophage polarization promotes proliferation and inhibits apoptosis in KGN cells. A Schema of the NPs-treated macrophage-KGN cell coculture model. B Representative images and quantification of EdU (+) in KGN cells. Scale bar = 50 μm. *P < 0.05, **P < 0.01. C CCK8 results of KGN cells in different groups. *P < 0.05, **P < 0.01, ***P < 0.001 vs. the CeO2 group; #P < 0.05, ##P < 0.01 vs. the CeO2 + RSV group. D RT-PCR analysis of Bcl2/Bax in different groups. E Western blot analysis of Bcl2/Bax in different groups. F Apoptosis of KGN cells in each group was detected by flow cytometry. n = 3, *P < 0.05, **P < 0.01, ***P < 0.001

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