Fig. 3From: Nanocomposites based on nanoceria regulate the immune microenvironment for the treatment of polycystic ovary syndromeCeO2@RSV-induced macrophage polarization promotes proliferation and inhibits apoptosis in KGN cells. A Schema of the NPs-treated macrophage-KGN cell coculture model. B Representative images and quantification of EdU (+) in KGN cells. Scale bar = 50 μm. *P < 0.05, **P < 0.01. C CCK8 results of KGN cells in different groups. *P < 0.05, **P < 0.01, ***P < 0.001 vs. the CeO2 group; #P < 0.05, ##P < 0.01 vs. the CeO2 + RSV group. D RT-PCR analysis of Bcl2/Bax in different groups. E Western blot analysis of Bcl2/Bax in different groups. F Apoptosis of KGN cells in each group was detected by flow cytometry. n = 3, *P < 0.05, **P < 0.01, ***P < 0.001Back to article page