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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Nanocomposites based on nanoceria regulate the immune microenvironment for the treatment of polycystic ovary syndrome

Fig. 5

Effects of CeO2@RSV on ameliorating ovarian function and endocrine disorders in PCOS mice. A Cytological assessment of vaginal smears after inducing PCOS and treatment with NPs. B–D Serum levels of T, E2 and LH in the indicated groups. E The number of cystic follicles in the ovaries of the mice in the indicated groups. F The number of corpora lutea in the ovaries of the mice in the indicated groups. n = 5, *P < 0.05, **P < 0.01, ***P < 0.001. G Representative HE staining of ovarian sections from the experimental mice. Scale bar: 200 µm. H, I Glucose tolerance tests and AUCs of the experimental mice. n = 5, *P < 0.05, **P < 0.01, ***P < 0.001 vs. the CeO2 group; #P < 0.05, ##P < 0.01 vs. the RSV group. &P < 0.05 vs. the CeO2 + RSV group

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