Fig. 6
Anti-inflammatory mechanism of CeO2@RSV evaluated by transcriptome. A Volcano plots showing the genes regulated by treatment with CeO2@RSV. B Clustered heatmap of representative inflammation-related genes (fold change ≥ 2.0 and p < 0.05). C Bar plot of biological processes of differentially expressed genes between the M1 and CeO2@RSV groups. D KEGG pathway enrichment analysis of the differentially expressed genes between the M1 and CeO2@RSV groups. E The protein expression of STAT3/p-STAT3, NF-κB/p-NF-κB, Erk1/2/p-Erk1/2, and MAPK/p-MAPK was detected by western blotting. n = 3, *P < 0.05, **P < 0.01, ***P < 0.001 vs. the M1 group