Fig. 5

Increased cardiac function and reduced infarct size following PDGF-BB-primed MSC transplantation by UTMD. (A) Representative echocardiogram of rat hearts in various groups at baseline (before MI) and 30 days post-MI. (B-E) Quantification analysis of cardiac function of LVEF and LVFS. (F) Representative images of Masson’s trichrome staining of heart sections. Bar, 5 mm (G-H) Quantitative measurement of the scar size and LV wall thickness in various groups. (I) Masson trichrome staining at the border zone. Bar, 20 μm. (J) Quantitative analysis of interstitial fibrosis in perimyocardial infarction in rats among the different groups. Values are the mean ± SEM. Significant differences were determined by using one-way ANOVA. N = 5/group. *p < 0.01 vs. MI; # p < 0.01 vs. MI-MSC-vehicle