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Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: Synergetic regulation of cancer cells and exhausted T cells to fight cold tumors with a fluorinated EGCG-based nanocomplex

Fig. 4

In vitro co-regulation by decreasing PD-L1 expression and mitigating T cells exhaustion using FEGCG/FPEI@siTOX NPs. (A) Apoptosis/necrosis ratio of different treatments in 4T1 cells. (B) PD-L1 expression of different treatments in 4T1 cells under IFN-γ stimulation in 4T1 cells. (C) Flow cytometry analysis of the percentage of PD-1+ Tim-3+ cells after different treatments in exhausted T cells. (D-E) TOX and Ki67 expression after different treatments in exhausted T cells

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Journal of Nanobiotechnology

ISSN: 1477-3155

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