Fig. 4

A Photographs of the skin wounds of various groups on day 0, 3, 7, 11and 14 (Scale: 10 mm). B Wound closure analysis from the existing wound area on day 3, 7, 11 and 14. C H&E staining of the wound sections on day 3, 7 and 14 (Scale: 100 μm). D Masson staining of the wound sections on day 7 and 14 (Scale: 50 μm). E Semi-quantification of skin granulation tissue thickness on day 7. F Collagen volume fraction of the wound sections on day 7. All data are presented as mean ± SD, *p < 0.05, **p < 0.01, ****p < 0.00001, n = 3