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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: A candidate nanoparticle vaccine comprised of multiple epitopes of the African swine fever virus elicits a robust immune response

Fig. 7

NanoFVax enhanced cellular immune responses in vivo. Percentage of splenic CD4 + (A) or CD8 + (B) T cells determined by flow cytometry. The response of different groups after in vitro stimulation, IFN-γ (C) and IL-4 (D) spot-forming cells and statistical analysis. Images were acquired and quantified using an ELISpot reader. E Cell proliferation was detected by MTT assay. NanoFVax induced significant cell proliferation compared to control. (n = 3), the data in 5A-5C are shown as the mean and standard deviation (mean ± SD). *p < 0.05; **p < 0.01; ***p < 0.001, ****p < 0.0001

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