Fig. 2

EF-sEVs promoted better functional behavioral recovery after SCI in rats. A The surgical processes and spinal cord compression. B Basso, Beattie, and Bresnahan (BBB) limb function scores at different times after SCI. C Representative footprints of an animal walking 4 weeks after SCI. Stride length analysis (right) of different groups. Black: front paw print; red: rear paw print. D Hindlimb vertical standing in rats after a 4-week recovery period postinjury. E Gross morphology of spinal sections; the area in the dotted line represents the extent of the scar. F Representative Nissl stainings of coronal sections of the spinal cord in different groups. Scar bar = 100 μm. G Representative HE images of spinal cord longitudinal sections 4 weeks postinjury in different groups. Scar bar = 500 μm. Statistical analysis was performed using a one-way analysis of variance. *P < 0.05, ***P < 0.001