Fig. 1
This figure was created with BioRender.com
Two classifications of EVs. A According to the origin of EVs, they can be classified as exosomes, microvesicles and apoptotic bodies. Exosomes are formed by early endosome formation, MVB development, plasma membrane transportation fusion and exocytosis. Microvesicles are formed by ectocytosis of the plasma membrane and apoptotic bodies are formed directly by means of membrane blebbing of apoptotic cells. B According to the particle size, EVs are divided into sEVs and lEVs