Fig. 4
From: Zn-Shik-PEG nanoparticles alleviate inflammation and multi-organ damage in sepsis
Therapeutic efficacy of the Zn-Shik-PEG NPs against LPS-induced sepsis in mice. (A) Experimental procedures for the LPS-induced sepsis mouse model. (B, C) Survival and clinical score analysis of the mice. (D, E) Body temperature change and thermographic images of mice in different treatment groups. (F, G) The level of pro-inflammatory cytokine TNF-α (F) and IL-6 (G) in the serum of septic mice. (H) Distribution of Cy5.5-labelled Zn-Shik-PEG NPs in main organs. Data are presented as mean ± SD (n = 3, 6). *p < 0.05, ** p < 0.01, and ***p < 0.001