Fig. 1

Construction and characterization of GHHM microspheres. A Microsphere observation in the light field, scale bar = 100 μm. B Distribution of particle size at different flow rates ratios. C SEM images of G, GHH and GHHM microspheres, scale bar above = 50 μm, below = 25 μm. D FTIR analysis of HA-His. E EDS spectrum of GHHM microspheres. F SEM Mapping of GHHM microspheres, scale bar = 50 μm. G Release curve of Mg²⁺. H Degradation curves of G, GHH and GHHM microspheres in PBS. I Dissolution curves of G, GHH and GHHM microspheres