Skip to main content
Fig. 10 | Journal of Nanobiotechnology

Fig. 10

From: A novel “prime and pull” strategy mediated by the combination of two dendritic cell-targeting designs induced protective lung tissue-resident memory T cells against H1N1 influenza virus challenge

Fig. 10

Measurement of M2e-specific antibodies and protection against influenza virus challenge in Study 2. ELISAs were performed to measure M2e-specific serum IgG (A), IgG1 (B), IgG2a (C) and the ratio of IgG1/IgG2a (D). The lung IgA (E) and IgG (F) antibodies were also determined. The mice were then challenged at a dose of 2 LD50 of H1N1 virus, and the survival rates (G) and body weight gains (H) were recorded for 14 days. On Day 5 post challenge, the lung samples were collected, and virus titers were determined by qRT‒PCR analysis (I). (n = 4, *P < 0.05, **P < 0.01, ***P < 0.001, ns, not significant)

Back to article page

Journal of Nanobiotechnology

ISSN: 1477-3155

Contact us