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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Carbon dot nanozymes as free radicals scavengers for the management of hepatic ischemia-reperfusion injury by regulating the liver inflammatory network and inhibiting apoptosis

Fig. 5

Biocompatibility of C-dots. The viability of L-02 cells was assessed after incubation with C-dots for 24 h (A) and 48 h (B). (C) The ratio of hemolysis in the subgroups. (D) Distribution of cell apoptosis and necrosis in L-02 cells as indicated by FACS results. (E) Assessment of the toxicity of C-dots to vital organs (heart, liver, spleen, lung, and kidney) in vivo, conducted 24 h following intravenous injection. Scale bar: 50 μm. (F) Changes in weight of typical mice 24 h after being administered with C-dots. (G) Levels of liver function markers, such as AST and ALT, in the serum. (H) Serum levels of BUN and CRE serve as indicators of kidney function. (I-M) Blood values in mice that were either intravenously treated with C-dots or normal animals (the control group), 24 h after injection

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