Fig. 2From: Evidence of brain target engagement in Parkinson’s disease and multiple sclerosis by the investigational nanomedicine, CNM-Au8, in the REPAIR phase 2 clinical trialsATP and Phosphorylation Potential Equilibration in REPAIR Clinical Trials. Pre-specified integrated analyses of REPAIR-MS and REPAIR-PD values of the exploratory endpoints, (a) Percent change in β-ATP from baseline to end-of-study and (b) Percent change in phosphorylation potential from baseline to end-of study, plotted against baseline values for β-ATP and phosphorylation potential, respectively. Individual values for REPAIR-PD participants (n = 13) are shown as light green triangles; individual values for REPAIR-MS participants are shown as dark green diamonds. Linear regression line (orange) and 95% CI (dashed curves) are shownBack to article page