Fig. 7

TAMs depletion largely abolished the synergetic anti-tumor efficacy of CNH-PG-mPT and BMS-1. See Table 2 for animal grouping and treatments. A Illustration of the experimental procedure. B Graft tumors collected at the end of therapy. C, D Tumor growth over the therapeutic period. E Average rates of tumor growth. F Tumor weights taken at the end of therapy. F Mφ + indicates mice without macrophage depletion; Mφ− indicates mice depleted of macrophages. Values are means ± standard deviation (SD). (n = 6, ^#,&,*p < 0.05, ^##,&,**p < 0.01)