Fig. 8

Cell proliferation and death profiles in the tumors with or without TAMs depletion. A Tumor tissue sections showing HE staining. B–D Tumor tissue sections showing IHC staining of PCNA and Ki67 (markers of cell growth) and cleaved caspase 3 (marker of cell death). Staining of PCNA, Ki67 and cleaved caspase 3 appeared as dark brown spots. Mφ + indicates mice without macrophage depletion; Mφ− indicates mice depleted of macrophages