Fig. 4

In vitro MRI of NO^·@PLT. (A) T1-weighted images (T1WI). The concentration was 0.015 g/mL for Agar, for PLT, 1.0 mg/mL for nano NO^· micelles, and 1.0 mg/mL for NO^·@PLT (calculated by nano NO^· micelles). (B) The changes in signal intensity as indicated by T1WI/T2WI of panel (A). (C) 3D image of tube and MR images of agar, PLT, nano NO^· micelles, and NO^·@agar. (D) The ratio of signal intensity in T1WI (core)/ (outer layer) in each group. (E) Correlation of NO^·@PLT concentration with T1WI signal intensity (the inset shows the signal intensity in T1WI of NO^·@PLT with different concentrations). **P < 0.01. No significant difference, n.s