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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Traditional Chinese medicine inspired dual-drugs loaded inhalable nano-therapeutics alleviated idiopathic pulmonary fibrosis by targeting early inflammation and late fibrosis

Fig. 2

The characteristic of AS_LIG@PPGC NPs. (A). The TEM image of naked NPs, AS@PPGC NPs, LIG@PPGC NPs, and AS_LIG@PPGC NPs. Scale bar = 100 μm. (B). The sizes of naked NPs, AS@PPGC NPs, LIG@PPGC NPs, and AS_LIG@PPGC NPs mearsured by DLS.(n = 3) (C to D). The encapsulation efficiencies of AS and LIG in AS_LIG@PPGC NPs. (E). Cell viabilities of of TGF-β1 treated L-929 cells incubated with AS_LIG@PPGC NPs different concentrations. (F). CLSM images of time-dependent cellular uptake of AS_LIG@PPGC NPs in TGF-β treated L-929 cells, Scale bar = 20 μm. The results were expressed as the mean ± SD (n = 3). (G). Flow cytometry analysis of uptake efficiencies in TGF-β1 treated L-929 cells. (H to I). Penetration of NPs with and without PEG coating in an artificial mucus model. The results were expressed as the mean ± SD (n = 3)

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Journal of Nanobiotechnology

ISSN: 1477-3155

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