Fig. 9From: New insights into nanotherapeutics for periodontitis: a triple concerto of antimicrobial activity, immunomodulation and periodontium regenerationSchematic illustration of periodontitis treatment by immunomodulatory and periodontium regeneration. A Schematic of PssL-NAC NPs regulates ROS levels exerts different effects on tissue regeneration. Reprinted with permission from Ref. [153] Copyright Elsevier. B Schematic illustration of TNPs inhibit macrophage-osteoclast differentiation, suppress DCs maturation and regulatory effector T cells. Reprinted with permission from Ref. [154] Copyright ElsevierBack to article page