Fig. 6

Effects of PS-MPs plus HFD treatment on cell subsets and biological pathways activation in MPs. A UMAP of mononuclear phagocytes colored by four treatment groups (left) and PT cell subsets (right). B The proportion of mononuclear phagocyte subsets in the ND and HFD groups (left) and four treatment groups (right). C Heatmap of the top 10 DEGs among mononuclear phagocyte subsets according to log fold changes. D Violin plot of the top 3 DEGs among mononuclear phagocyte subsets according to log fold changes. E Pseudotime trajectory analysis colored by mononuclear phagocyte subsets at varying pseudotime stages (right) and by individual mononuclear phagocyte subsets (left). F KEGG enrichment analysis of upregulation pathways of mononuclear phagocytes in PS-MPs group vs. ND group. G KEGG enrichment analysis of upregulation pathways of mononuclear phagocytes in PS-MPs plus HFD group vs. HFD group