Fig. 3
From: In vivo therapy of osteosarcoma using anion transporters-based supramolecular drugs
BTFPTU triggers transcriptional reprogramming of HOS cells. (A) Volcano plot of RNA sequencing (RNA-seq) analysis on HOS cells treated with either PBS or BTFPTU for 24 h. (B) The differential gene clustering heatmap of RNA-seq analysis. (C) The network of enriched terms of RNA-seq analysis. The left figure was colored by P-value and terms containing more genes tended to have a more significant P-value. The right figure was colored by cluster ID and nodes share the same cluster were typically close to each other. (D) KEGG enrichment of RNA-seq analysis. (E) GO enrichment of RNA-seq analysis. p < 0.05 is defined as having a significant difference for comparison with the control group