Schematic illustration of HA/LF@EMO-NPs Gel for CNP therapy. A Scheme showing the preparations of HA/LF@EMO-NPs Gel. B HA/LF@EMO-NPs Gel is administered rectally and hitchhikes sequentially on intestinal epithelial cells, prostate epithelial cells and macrophages to be delivered to the ectopic lesion, ultimately relieving CNP