Fig. 5
AAV-13A7-Fc administration ameliorated acute DSS-induced colitis. Mice (n = 10) received 1011 vg of AAVnano coding for 13A7-Fc or 14D5-dimHLE and three weeks later they were given 2.5% DSS in drinking water for five days. Mice were switched to regular water for eight additional days and colons were collected at the end of the study. A Disease activity score (DAI). B Colon macroscopic appearance. C Histopathological analysis of colon stained with hematoxylin and eosin staining. Mean ± SEM are shown. Statistical comparison Two-way ANOVA (A) or one-way ANOVA (B, C) was performed with *p < 0.05 and **p < 0.01. One representative experiment out of three is shown