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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: Administration of an AAV vector coding for a P2X7-blocking nanobody-based biologic ameliorates colitis in mice

Fig. 6

AAV-13A7-Fc administration ameliorated chronic DSS-induced colitis. Mice (n = 10) received 1011 vg of AAV coding for 13A7-Fc or 14D5-dimHLE and received three cycles of 2.5% DSS in drinking water for 5 days followed by regular water for 15 additional days. Disease activity score (DAI) curves and cumulative and mean DAI scores are shown. Mean ± SEM are shown. Statistical comparison two-way ANOVA (top) or one-way ANOVA (bottom) were performed with *p < 0.05 and **p < 0.01 and ***p < 0.001. A representative experiment out of three is shown

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