Fig. 3

ROS generation and in vitro MRI. TEM images of FCP (a) and HCF (b) with 10 mM GSH incubation. c Cumulative release behavior of β-lap from HCF@β-lap nanosystem after treatment with various concentrations of GSH upon 48 h. d The release of Fe element from HCF nanocomposites in different GSH concentrations. e H₂O₂ cumulative release profile (CaO₂ = 10 µg mL⁻¹). f O₂ concentration measurement in PBS (10 mM, pH = 7.4) (CaO₂ = 100 µg mL⁻¹). g Schematic diagram of H₂O₂, O₂ and ·OH generation h UV–vis absorption spectra of MB degradation in different solutions [Fe] = 0.5 mM, [H₂O₂] = 8 mM, [NaHCO₃/5% CO₂] = 25 mM). i MB degradation by ·OH generated from different concentration of GSH-treated HCF@β-lap (100 µg mL⁻¹) plus H₂O₂ (8 mM) and j different concentration of H₂O₂-treated HCF@β-lap (100 µg mL⁻¹) plus GSH (1 mM). [NaHCO₃/5% CO₂] = 25 mM. k T₂-weighted images