Fig. 10
From: The application of nanoparticles-based ferroptosis, pyroptosis and autophagy in cancer immunotherapy
Copyright 2019, American Chemical Society publishing group
A i: Schematic representation of LipoDDP synthesis ii: TEM image and hydrodynamic size distribution of LipoDDP (scale bar: 100 nm). iii: Optical living imaging of 4 T-1 tumor-bearing mice after treated with Dir-labeled LipoDDP at different time periods. B Illustrative diagram of tumor cell pyroptosis triggered by DAC/chemotherapeutics C Pyroptosis of tumor cells improved immune response of chemotherapy. i: Representative flow cytometric analysis of CD8 + and CD4 + T cells gating on CD3 + cells in the tumors. ii: Representative flow cytometric analysis of CD80 + CD86 + cells gating on CD11c + cells within TDLN. iii: Representative flow cytometric analysis of CD44 + CD62L + cells gating on CD8 + cells within the spleen.