Fig. 8
From: The application of nanoparticles-based ferroptosis, pyroptosis and autophagy in cancer immunotherapy
Copyright 2022, WILEY publishing group
A Scheme of GOx-Mn/HA synthesis and biomineralized two-enzyme nanoparticles that regulate tumor glycometabolism inducing tumor cell pyroptosis and robust antitumor immunotherapy. B Multiple gene expression levels in tumors characterized by RT-PCR. C Tumor immune microenvironment (TIME) reprogramming. Ratios of DCs maturation in TDLNs; Ratios of CD3 + T cells in tumors; Ratios of CD4 + T cells in tumors; Ratios of CD8 + T cells in tumors; Ratios of M1-like macrophage in tumors; Ratios of M2-like macrophage in tumors; Ratios of MDSCs in tumors; Ratios of Treg cell in CD4 + T cells.