Fig. 8From: Mesenchymal stem cell-derived extracellular vesicles exert pro-angiogenic and pro-lymphangiogenic effects in ischemic tissues by transferring various microRNAs and proteins including ITGa5 and NRP1Lymphangiogenesis in ischemic tissues after treatment with MSC-EVs in vivo. A Representative immunofluorescence images of gastrocnemius muscle sections harvested from ischemic (I) and non-ischemic limb (N) of vehicle- or MSC-EV-treated mice at 21 days post HLI. B Quantification of Lyve 1 and CD31-stained vessels in tissues of vehicle- or MSC-EV-treated animals. Data are expressed as ratio of ischemic (I) to non-ischemic (N). Student t-test, comparison to vehicle-treated samples (**P < 0.01)Back to article page