Fig. 6
From: Minocycline-loaded nHAP/PLGA microspheres for prevention of injury-related corneal angiogenesis
Evaluation of MINO@PLGA safety on organ histopathology and systemic blood parameters. A H&E of major organs in rats from different groups at 7 days after corneal alkali burn (scale bar: 100 μm). B Biochemical indicators in the orbital venous blood of rats from different groups at 7 days after alkali burn. Creatinine (Cre) reference range: 19.43–64.97 mmol/L. Urea (Ure) reference range: 2.08–7.75 mmol/L. Alanine aminotransferase (ALT) reference range: 33.7–98.7 U/L. Aspartate aminotransferase (AST) reference range: 69.7–322.9 U/L (n = 6)