Fig. 2

Hypo-ADSC-Exos promote the proliferation, migration, and tube formation in HUVECs in vitro. A Cell proliferation of HUVECs measured by EDU staining. Scale bar = 200 μm. n = 5. B Representative images of tube formation in HUVECs treated with PBS, Norm-Exos or Hypo-Exos. Scale bar = 200 μm. n = 5. C Quantitative analysis of the tube formation assay in the normoxia and hypoxia groups. D Extracted exosomes promoted cell migration as determined by a scratch test at 0 h, 8 h, 16 h and 24 h after treatment. n = 5. E Quantitative analysis of the migration rate of HUVECs (*p < 0.05; **p < 0.01; ***p < 0.001)