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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Quercetin-loaded mesoporous nano-delivery system remodels osteoimmune microenvironment to regenerate alveolar bone in periodontitis via the miR-21a-5p/PDCD4/NF-κB pathway

Fig. 2

Quercetin sustained-release system strengthened alveolar bone regeneration and relieved local inflammation in a rat alveolar bone defect model with periodontitis. A Scheme illustration of the experimental design used for the animal study. B Micro-CT reconstruction images of the alveolar bone tissue. C Quantitative analysis of the newly formed alveolar bone tissue. D Immunofluorescence staining of iNOS in samples collected in 1 week. E Immunofluorescence staining of CD31 and OPN in samples collected in 8 weeks. F Quantitative analysis of the mean fluorescence intensity of iNOS, CD31and OPN according to the immunostaining patterns shown in (D and E). (ns, no significant difference; *p < 0.05; **p < 0.01; ***p < 0.001; Data are represented as the mean ± SEM, n = 3)

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Journal of Nanobiotechnology

ISSN: 1477-3155

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